BIOL122 Human Biological Science-audience is health professionals


Vodcast Assessment
You will have the opportunity to describe the pathophysiology and pharmacological management for a person/client with type 1 diabetes mellitus, type 2 diabetes mellitus gestational diabetes or extrinsic asthma. We expect you to show your understanding by making explicit the links between the pathophysiology, clinical manifestations and pharmacological management of the person/client’s disease; your target audience is health professionals (e.g., Nurse, paramedic, midwife. At the beginning of your Vodcast, you need to set the scene within the first minute by introducing your person/client. Following this introduction, proceed to answer the following questions.

Diabetes Mellitus 

Question 1a. Explain how BOTH of the following are different in your patient in comparison to a healthy, non-diabetic person.
(i) insulin synthesis and secretion and
(ii) insulin binding to its target cells

Question 1b. Explain the benefits of monitoring HbA1c in the management of your person’s/client’s disease.

Question 2a. Neuropathy and myocardial infarction are long-term consequences of poorly managed diabetes. Explain why they are more likely to occur in patients suffering from diabetes than in the non-diabetic population.

Question 2b. Both metformin and insulin may be used in the management of diabetes mellitus. By making meaningful references to your patient,

(i) Choose the one that is the most appropriate for the treatment of your patient,
(ii) Describe its mechanism of action, and
(iii) Explain why the drug you selected is the most appropriate for the treatment of your patient.

Question 3. Define insulin resistance and explain the link between apple-type obesity and insulin resistance.

Question 1. Two of the major pathological changes that affect the airways during an asthma attack are bronchoconstriction and increased mucus production in the airways. By reflecting on the pathophysiology of bronchial asthma, explain how these pathological changes arise in your patient. In your explanation, you are expected the outline the significance of a specific allergen that may trigger an acute asthma attack.

Question 2a. The clinical manifestations of an acute asthma attack may include the following signs and symptoms:

Cough Airway oedema
Hypoxia Increased respiratory rate
Wheeze Increased heart rate
Tight chest Dyspnoea

Choose one clinical manifestation from GROUP A and one from GROUP B and relate them to the underlying pathophysiology for your person. In your answer, explain the link between an acute asthma attack and both signs/symptoms you chose.

Question 2b. Salbutamol and corticosteroids are used in the management of asthma. Explain the mechanism of action of these two medications and their benefits in managing your patient’s condition. 

Question 3.

Adequate education of patients suffering from/prone to asthma attacks is important in asthma management. Briefly summarize the advice you would give to your patient in respect to

i. Corticosteroid administration
ii. Strategies relating to effective prevention and management of their acute asthmatic episodes.

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